Cause - Why

xenoestrogens cause fibrocystic breast disease


Correct Dose of Progesterone


No Estrogen

Thyroid Receptor Depression with Estrogen Use

Testing for progesterone in the body


Frequently Asked Questions

Summary for care of Fibrocystic Breast


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Xenoestrogens cause Early Puberty in Children

Xenoestrogens cause Early Puberty in Children
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by Elizabeth Smith, M.D.

A True Cure



Fibrocystic breast condition is easily treated permanently using "over the counter" progesterone cream and avoiding environmental estrogens (chemical estrogens). It is simple, cost effective, and effective. (kvc)


John Lee, M.D. has treated fibrocystic breast disease with success for decades. He writes: "Muriel came into my office at age 50 with exercising womanmultiple scars on both breasts from seven different excision biopsies, all of which found dense fibrocystic breast disease. She readily admitted chronic cancer anxiety. In addition, she suffered from reactive hypoglycemia. She performed breast self-exams routinely and the finding of each new lump aroused fear and trepidation because of her cysts. Now, at menopause, she wanted hormone replacement therapy. Instead of traditional HRT (hormone replacement therapy), I recommended physiologic dosages of progesterone without estrogen. Her fibrocysts disappeared within six months, her sense of energy and libido returned, her hypoglycemic episodes became a thing of the past, and her tennis game improved. Further , serial density (BMD) tests over the subsequent ten years remained good, and her cancer anxiety faded away with the improvement in her breasts."

Go to this website that explains very succinctly how to cure fibrocystic breast permanently by using lifestyle changes and a simple nutritional changes. Chemicals and herbs that mimic estrogen commonly found in toiletries and cosmetics are causing the fibrocystic breast. These are collectively known as xenoestrogens or foreign estrogens or hormone disruptors.

prevent breast cancer
"Natural Progesterone prevents Breast Cancer."

John Lee, M.D.

See section QandA for further details. Get the book! What Your Doctor May Not Tell You About Breast Cancer



Cure Fibrocystic Breasts

NO Surgery!

Dr. Lee Treats Fibrocystic Breasts Successfully


Dr. Lee further writes in his book:

"Many women present themselves to their doctors with breast swelling or tender, painful breasts occurring each month before their menstrual periods. Exam by palpation may find exquisitely tender lumps in the breast. Even coffee exacerbates fibrocystic breast diseasethough he knows with almost 100-percent certainty that the problem is due to fibrocystic breast disease, the doctor is aware of the liability of overlooking any breast lump and therefore often orders a mammogram (especially painful in this condition). Mammogram readings are often couched in terms of caution and the advice to rule out potential underlying cancer. (Cancer lumps in breasts are rarely if ever painful.) A trial of Vitamin E and avoiding caffeine and other methyl xanthines (coffee, tea, colas, chocolate) may have little or no result. Attempts at needle aspiration of the cyst are often bungled, sometimes causing painful bruising, and lead to a referral to a surgeon predisposed to surgery, who brings up the prospect of cancer and advises surgical removal of the offending cyst/tumor. If "merely" a cyst is found (and removed), the patient is supposed to feel grateful. She usually receives no other medical treatment for her fibrocystic breast disease other than a suggestion to try warm packs and put up with her painful monthly experiences.




"I cannot recall a case in which the result (from treatment) was not positive."

John Lee, M.D.



If she makes the rounds of enough doctors, she will come across someone who wants her to take a drug (usually a testosterone analog) to suppress her excess estrogen. Besides being expensive, she finds that a few, mostly masculinizing side effects are part of the bargain: acne, seborrhea, hair growth on the face and body, male pattern baldness, lower pitch to voice, vaginal dryness, and sagging smaller breasts. Most women find the treatment is worse than the disease.


  From my women patients, I learned that fibrocystic breasts were most often a sign of estrogen dominance; relatively high estrogen and low progesterone. In my experience, using natural progesterone routinely solves the problem. I also recommend adding vitamin E in dosages of 600 IU at bedtime, supplemental magnesium (300 milligrams a day), and vitamin B6 (50 milligrams per day)*. I cannot recall a case in which the result was not positive. Once the cysts have cleared up, you can reduce the progesterone dose to find the smallest dose that is still effective each month and continue the treatment as needed through menopause. This treatment is simple, safe, inexpensive, successful, and natural."

Xenoestrogens (foreign estrogens) as the Primary Culprit

"Xeno" means foreign. Estrogen is the female hormone that causes breast development and dominates the first part of the menstrual cycle. A hormone is a chemical messenger. The problem is that there are 100,000 chemicals in use in the United States, and some of these synthetic chemicals have estrogen like effects (xenoestrogens). Scientists now believe that xenoestrogens can cause fibrocystic breast disease and breast cancer. Too much intake of estrogen or xenoestrogens has been labeled as estrogen dominance by Lee, MD. And synthetic estrogen or chemicals that mimic estrogen (xenoestrogen) is NOT the same as Natural Estrogen. According to the Physician's Desk Reference, synthetic estrogen will cause an increase in endometrial cancer and breast cancer.

United States and Canadian ranchers routinely give synthetic estrogen to their cattle. As a result of the estrogen, the cattle bloat and retain water. Thus, the estrogenized cattle meat is heavier and more tender. Also the fat begins to build up in the animal and marble through the meat. The ranchers can get more money for their cattle because the meat weighs more and is more tender. The ranchers give estrogen to their cattle intentionally for the bloating fattening effect of estrogen, and faster growth.

However, when a women comes down with these symptoms especially when the doctorexcercising gives her estrogen, the doctors "don't know why" she retains water and has fat build up around the hips. The doctors label this effect as Premenstrual Syndrome ( PMS ). There is evidence that synthetic estrogens and synthetic progestins build up in the fat and the body has difficulty in excreting it.

The ranchers also give estrogen to cattle and farmers give estrogen to chicken with the full knowledge that the estrogen will cause the animal to grow and mature faster. Now, Time magazine has cited the 1997 landmark study of 17,000 girls aged 8. 15% of these girls are going through early puberty and sprouting breast buds and pubic hair. The Time magazine cover story, October 30, 2000, cites that some chemicals mimic estrogen (xenoestrogens) and blames these chemicals for the early growth spurt of girls and early puberty.

The European Union has banned Canadian and United States beef from being imported citing worries about increasing the rate of breast cancer in Europe.

For more information on xenoestrogens, see Cause and Xenoestrogens.
See a new updated website on fibrocystic breast disease - breast cysts.



twins do not have increased risk
"In my experience, using natural progesterone routinely solves the problem (fibrocystic breast disease)."

John Lee, M.D.



See the Cornell University Website on Xenoestrogens (foreign estrogens, environmental estrogens) Contributing to Breast Cancer and Fibrocystic Breast Condition

Suzanne M. Snedeker, PhD of Cornell University has quite a nice website explaining how environmental estrogens cause breast cancer. Xenoestrogens that mimic estrogen bind to the estrogen receptor. I believe that too much estrogen from xenoestrogens also cause cysts in the breast disease. See the website here that includes a very nice video presentation.


Severe Fibrocystic Breasts - I feel almost 100% better in just a few weeks.

I bought progestelle about two months ago for severe fibrocystic breasts. I have drastically made changes in line with your recommendations. I feel almost 100% better in just a few weeks. This is my second month using the product and about mid-way through my cycle (ovulation?) I had breakthrough bleeding. It was light red, more brown, not heavy amount and mostly in the morning for about three days. Now I am on day 32 of my cycle and have not gotten my period (I assure you I am not pregnant). Before progestelle my cycles would be close to 45 days. Last month I (blissfully...with no PMS) started my period on the 26th day of my cycle.

I have only been using one dropperful of progestelle before bed. Should I stop for a few days to see if my period begins? Do you think that "breakthrough bleeding" was my period? I usually have a very heavy amount of blood for five days. Will I be at risk for endometriosis if I don't get my period and "shed" that lining? I would appreciate your opinion on this! Thanks so much for all the information you have made available. Not a day goes by (not a minute) that I don't feel utter gratefulness for being pain-free. I just want to continue making positive decisions about my body. I can't help but wonder if it is hormonely confused right now!

My children have noticed me being fibrocystic breast disease pain-free. I couldn't hug them tight because my breasts would hurt so badly. Now they run up and give me long, bear hugs... I can play jump-rope with them (that used to hurt just thinking about). I am not on edge anymore. The progestelle has helped me be the person I really am (not jacked up on estrogen), I am relaxed and much more patient with everyone. I have more energy. I am so happy and grateful. But, most of all I am not fearful anymore. Being in pain is frightening and debilitating emotionally and physically. I have spent so much money trying to find a "cure" for fibrocystic breasts. The bulk of the work is up to me. I'm willing to do it now that I know what to do. And that little glass bottle of Progestelle is the most valuable thing in my house (besides my family!).


Laura G.

Charles Town, Alabama

Oct. 16, 2009


I am happy to report a huge relief from fibrocystic breast disease & ovarian pain from cysts.

Dear Dr.,

I am now into my third month on natural progesterone cream, avoiding xeno & phyto estrogens as much as possible, and taking the recommended supplements as per your suggestions in the little blue booklet .

I am happy to report a huge relief of fibrocystic breast pain & ovarian pain from cysts. Two months ago I could not even lay on my side or stomach. Now there is no problem. The endometrial pain I have suffered with for 10 years is greatly diminished, I feel clearer in my thinking, my energy is coming back, my hair is indeed getting thicker, and I am feeling a new joy in life and very hopeful of even more improvements to come.

Considering that half my life was consumed with endometrial pain (from ovulation, until menstruation), combined with horrible PMS (which I just thought was NORMAL until I read your literature!) I NOW have an extra 2 weeks every month that I can actually function like a normal person rather than being curled up in bed with pain & exhaustion written all over my face.

Please feel free to use my experience in any of your product promotion. I am starting a grass-roots movement to share my experiences with xenoestrogens to educate other women, and would like to know if you have literature you would like me to pass out when I have my first meeting. I am sharing simply my own experience, but I will definitely be telling them about Progestelle and your research.

Your work is amazing and important, and I want to thank you from myself and from the many women you have helped and will help due to your fantastic research for a new opportunity to live without fibrocystic breast disease pain, keeping our ovaries and learning proactively how to take charge of our own health.

With heart felt thanks,

Cindy H.

Sarasota, FL

Aug 28, 2009

*Whole grains also regulate hormonal levels due to their high levels of vitamin B and vitamin E, which have a beneficial effect on both the liver and the ovaries. In 1942, a researcher named Biskind found that B vitamin deficiency hindered the liver's ability to metabolize estrogen levels in both animal and human test subjects. The addition of B vitamin supplementation to the diet of women suffering from PMS, heavy menstrual bleeding, and fibrocystic breast disease helped to decrease the severity of their symptoms. Studies conducted at UCLA Medical School during the 1980s found that taking a specific B vitamin, pyridoxine B6, helped to relieve symptoms of menstrual cramps and PMS.

Research also conducted during the 1980s at Johns Hopkins University Medical Center similarly found, in several placebo controlled studies, that vitamin E is useful in reducing many PMS symptoms, as well as fibrocystic breast discomfort. Other studies have found that vitamin E supplementation reduced menopause related hot flashes, fatigue, and mood swings in 66 to 85 percent of the women tested, depending on the study. One additional study noted a decrease in the symptoms of vaginal atrophy in 50 percent of the postmenopausal women volunteers.

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