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Sources of Online Progesterone   Buying Your Natural Progesterone Virtually all Natural Progesterone is made from yams or soy. Soy and Yams contain a diosgenin which is a molecule that has the base molecule of progesterone. The progesterone cream should not contain any mineral oil. It should contain vegetable oil instead. The correct dosage should be 400-1000 mg/oz of progesterone. The progeterone cream should NOT contain Methyl Paraben, Propyl Paraben, Butyl Paraben or any of the related Parabens. by Elizabeth Smith, M.D. Many of the companies tout that their progesterone is made from yams or soy. However, that is the most economical way to make progesterone. All Natural Progesterone is made from yams and/or soy. These plants contain a disogenin which has the base molecule for progesterone. In processing, some parts of the diosgenin are cleaved off and progesterone is the result. Yam extract, a diosgenin, is not Natural Progesterone. Thus, some skin creams say that they contain a yam extract. According to Dr. Lee, these creams do not work well. A skin cream containing Mineral Oil will not work. The Mineral Oil will block the absorption of the Natural Progesterone. The skin cream should contain a vegetable oil instead. Be careful of toxic compounds in the skin cream. Much to my horror, one compound that we were recommending to my patients had Stearal Konium Chloride, an emulsifier. According to the University of Texas database ingestion of 3cc of Stearal Konium Chloride is enough to cause fatal convulsions in an adult human. Be careful of herbs used in the skin cream. Once again we used a skin cream on some of our post menopausal patients that caused their uterus to get bigger. We found that the company had used some herbs that were estrogenic in nature. Recently, Professor Sumpter in the U.K. discovered that Methyl Paraben, Propyl Paraben, and Butly Paraben are estrogen mimics and stimulate the estrogen receptor. His research was so disturbing that the European Union inquired of the European Cosmetics and Toiletry Association whether these common preservatives would increase the rate of breast cancer. The vast majority of hand lotions and gels contain this preservative. We found that many Natural Progesterone creams contain this preservative as well. The correct dose of progesterone in the skin cream is 400-1000 mg/oz. If the dose of progesterone is too low there is no clinical effect. If the dose is too high then the patients experience shortness of breath. If the dose is too high, the patients will also experience an emotional depression when the progesterone is stopped. In extreme cases, when the progesterone was 2,800 mg/oz, and used for several years, we have heard of some patients becoming mentally confused. The mental confusion was reversed when the patients stopped taking the cream for several months. Here is one vendor that we like: Women's Therapeutic Institute for Progesterone Cream Alternative Site for Progesterone Cream Alternative Site 2 for Progesterone Cream